Introduction: Acute appendicitis is one of the most prevalent abdominal surgical emergencies, and appendectomy, as the only treatment option, is one of the most common surgeries, with a high rate of negative exploration.
The primary goal of this study was to compare the accuracy and efficacy of CRP
versus TLC in diagnosing acute appendicitis.
Methods: A total of 200 patients were included in the trial, all of them were
diagnosed with acute appendicitis based on a WBC count and clinical examination
and were scheduled for appendectomy. Before the operation, these patients'
serum CRP levels were calculated together with their WBC counts, but this
information was not used in the appendectomy decision-making process. All of
the appendixes that were excised were sent for histological testing.
Sensitivity, specificity, positive predictive value, negative predictive value,
and diagnostic accuracy of serum CRP were 94.1 percent, 73.3 percent, 95.23
percent, 68.75 percent, and 91 percent, respectively, whereas WBC were 88.23
percent, 60 percent, 92.59 percent, 47.36 percent, and 84 percent.
To lower the rate of negative appendectomy, serum CRP should be used in
conjunction with other laboratory markers and clinical examination in the
diagnosis of acute appendicitis.
Author(s) Details:
Assistant Professor,
Dr. Bandana Kumari,
MBBS, MD, DGO, FCGP.
Department of Biochemistry, All India
Institute of Medical Sciences, Patna, Bihar, India.
Pawan Kumar,
Department of Radiology, Patna Medical College & Hospital, Patna,
Bihar, India.
Neha Chaudhary,
Department of Community and Family Medicine, All India Institute of Medical
Sciences Patna, Bihar, India.
Anil Kumar,
Department of Surgery, All India Institute of Medical Sciences Patna,
Bihar, India.
Achal Narain Roy,
Department of Biochemistry, Patna Medical College & Hospital, Patna,
Bihar, India.
Please see the link here: https://stm.bookpi.org/IDMMR-V10/article/view/5832
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