Assessment of Antibiotic Sensitivity Pattern of Bacterial Isolates in the Intensive Care Unit of a Tertiary Care Hospital in Eastern India| Chapter 9 | Issues and Developments in Medicine and Medical Research Vol.10

 Background: Nosocomial infections are a primary cause of morbidity and mortality in hospitalised patients, particularly critically sick patients in the intensive care unit (ICU), where a large number of medications are provided, resulting in the development of antibiotic-resistant microorganisms.

The study's goal was to determine the prevalence of common bacterial germs, as well as their medication sensitivity and resistance, in the ICU of an Eastern Indian teaching hospital.

A retrospective record-based study was conducted in the ICU of Hi- Tech Medical College and Hospital in Odisha, Eastern India, from November 2011 to October 2012. Patients who were clinically suspected of contracting an infection within 48 hours of being admitted to the ICUs were included in the study. Patients' clinically suspected laboratory samples were gathered and antibiotic sensitivity was assessed.

The rate of nosocomial infection was found to be 28.2 percent. Urinary tract infection was the most prevalent infection (54.9 percent). E. coli was the most prevalent isolate (52.7%), followed by P. mirabilis (15.4%) and Ps aeruginosa (14.4%). (13.2 percent). E. coli was very susceptible to Polymyxin B, Gatifloxacin, and Ceftriaxone, whereas it was highly resistant to Cephalexin, Cefadroxil, Tobramycin, and Prulifloxacin.

Conclusions: Resistance to third-generation cephalosporins and aminoglycosides was found in the majority of the bacterial isolates. Antibiotic susceptibility patterns must be monitored on a regular basis, and antibiotics must be used wisely to reduce nosocomial infection rates and antimicrobial resistance.

Author(s) Details:

Prof. Chaitali Pattanayak,
Department of Pharmacology, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.

Dr. Sunil K. Patanaik,
Department of Surgery, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.

Dr. Pratyay Pratim Datta,
West Bengal Health Service, India.

Prof. Parbaty Panda,
Department of Pharmacology, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India.

Please see the link here: https://stm.bookpi.org/IDMMR-V10/article/view/5823