Monday, 28 February 2022

A Recent Approach on Optic Disc Drusenoid Deposits with Hemifield Defects in a Patient with IgA Nephropathy | Chapter 24 | Issues and Developments in Medicine and Medical Research Vol. 9

 The study's goal is to describe forthcoming novel OCT and Humphrey visual field discoveries. Patients with IgA nephropathy (25-30%) develop end-stage renal disease within 20 years of diagnosis, but there is a lack of information and evaluation regarding visual disturbances. Here, we present a known IgAN patient with associated visual haziness who presented to our ophthalmology department [1].

A 20-year-old female patient who had previously been treated for skin rashes, hematuria, and abdominal pain 8 months ago reported vision disruption in her right eye for the past week. A clinical diagnosis of IgA nephropathy was deduced from skin biopsy findings of leukocytoclastic vasculitis and renal biopsy findings of glomerular mesangial cell hyperplasia.

In addition to early symptoms of papilledema, proteinuria appeared one month after administration of prednisolone 50 mg/day tapered for eight months. Visual acuity of 6/9 in the right eye and 6/6 in the left eye with normal colour vision were observed. Traditionally, hyperreflective powerful echoes in the optic disc were observed on OCT, while inferior hemifield abnormalities were found largely in the right eye on HFA.

The Wintrobe method revealed a total leucocyte count of 11720 cells/cu mm and an ESR of 60 mm/hr, as well as the presence of albumin, RBCs, and pus cells in urine analysis, as well as positive occult stool blood detection. The C3, C4, and ANCA tests all came back negative, and an ultrasound of the abdomen indicated fatty liver with mesenteric nodes. In conclusion, the linked early fundus manifestation of IgA nephropathy may be otic disc drusenoid deposits correlating with hemifield visual field abnormalities reported in the current case study.


Author(S) Details

S. K. Prabhakar
JSS Academy of Higher Education and Research, JSS Medical College Hospital, Mysore, Karnataka, India.

P. V. Priyamvada
JSS Academy of Higher Education and Research, JSS Medical College Hospital, Mysore, Karnataka, India.

View Book:- https://stm.bookpi.org/IDMMR-V9/article/view/5859

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