Hi-D immunophenotyping of COVID-19 patients' peripheral blood indicated a considerable shift in immune cell ratios, particularly between mature and immature neutrophils, which was linked to severity. Absolute numbers of lymphocyte subsets were also reduced differently in COVID-19 individuals depending on clinical severity, according to Hi-D FACS. Using Hi-D FACS to study immune responses in the context of clinical severity is a basis for overcoming the lack of an efficient antiviral immune response in COVID-19 patients with severe disease, and it can serve as a predictive biomarker for disease outcome and control.
Author(S) Details
K. Heydari
Stanford Medicine, Cell Therapy Facility, Stanford Health Care, USA.
View Book:- https://stm.bookpi.org/ETDHR-V3/article/view/5892
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