The Balance between Carbohydrate and Fat Utilization at Rest and in Progressive Intensity Exercise in the Insulin Resistence | Chapter 05 | Issues and Developments in Medicine and Medical Research Vol. 7

 The goal of this study is to look at how insulin resistance affects the balance of carbohydrate and fat utilisation at rest and during escalating intensity exercise. The use of a predetermined percentage of maximum VO2 for intensity control is a frequent characteristic of many research that examined substrate balance in people with insulin resistance, diabetes, and obesity.

Twelve sedentary male individuals were separated into two groups based on their insulin resistance index (>RI and RI) (HOMA-IR). Carbohydrate and fat utilisation at rest, the crossover point, the exercise intensity that elicits maximal fat oxidation (Fatmax), and carbohydrate and fat utilisation at Fatmax were all studied using indirect calorimetry. The MANN-WHITNEY test was used to compare all variables.

The Fatmax (37,357,99 vs. 39,813,84 percent VO2max) and Crossover points (40,087,19 vs. 40,675,12 percent VO2max) were not significantly different across the groups. At rest (0,0950,009 vs. 0,0690,028 g/min, 0,2440,082 vs. 0,2500,073 g/min, fat and carbohydrate, respectively) and at Fatmax (0,3970,087 vs. 0,2300,076 g/min, 0,6890,229 vs. 0,8670,222 g/min, fat and carbohydrate, respectively), no significant

Insulin resistance had no effect on the Crossover and Fatmax points, as well as the substrate balance at rest and at Fatmax.

Author(S) Details

Fabiano de Macedo Salgueirosa
Department of Physical Education, Federal University of Paraná, Curitiba - PR, Brazil.

Maria Gisele dos Santos
Department of Physical Education, Federal University of Paraná, Curitiba - PR, Brazil.

Richard B. Kreider
Exercise & Sport Nutrition Lab/Human Clinical Research Facility, Texas A&M University, USA.

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