Background: The care of patients with ureteral calculi has changed dramatically in recent years, with the conservative approach becoming the predominant focus, with the main advantage being reduced patient morbidity. Adjuvant medical expulsive therapy (MET) can be used in conjunction with the expectant method for distal ureteric stones to help with symptom relief and stone evacuation. By comparing Tadalafil and Tamsulosin, the current study aimed to find the single best monotherapy for medical expulsive therapy of distal ureteric stones.
A hospital-based
comparison study was conducted at the Department of Surgery of a tertiary care
hospital. A total of 120 cases with lower ureteric calculus were included in
the investigation. These 120 patients were then separated into two groups of 60
patients each, with each group receiving one of two medical treatments:
Tadalafil or Tamsulosin.
Results: Patients
treated with tadalafil had a substantially shorter time to expel calculi than
those treated with tamsulosin (13.1 vs 16.92 days; p0.05). On tadalafil,
complete ejection was noted in 86.7 percent of cases compared to only 63.3
percent on tamsulosin (p0.05). In patients treated with tamsulosin, mean
analgesic usage (2.69 vs 1.81; p0.05) and episodes of colicy pain (1.41 vs
0.43; p0.05) were considerably higher. Tamsulosin also needed more hospital
visits throughout therapy (2.56 vs 2.02 days; p=0.06), but the difference was
not statistically significant. There was no difference between the two
medications' adverse effect profiles.
Author(S) Details
Vipul Gurjar
SBKS MIRC, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
Bhavin Shah
SBKS MIRC, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
View Book:- https://stm.bookpi.org/IDMMR-V9/article/view/5858
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