Friday, 25 February 2022

A Revolutionary Saturation Pulse with a High Flip Angle on 7 T Time-of-Flight Magnetic Resonance Angiography | Chapter 19 | Issues and Developments in Medicine and Medical Research Vol. 8

 On 7 T time-of-flight magnetic resonance angiography (7T TOF-MRA), this study aimed to apply minimum-time variable-rate selective excitation (MinVER) to a presaturation pulse (PSP) with a high flip angle to achieve a superior vessel-to-tissue contrast (VTCR), short acquisition time, and minor off-resonance effect. The performance of an adjusted PSP modified by employing the 90° flip angle (FA)-MinVER in the 7 T TOF-MRA was evaluated using a signal profile and vessel-tissue contrast ratios, and it was compared to the traditional PSP and 45 FA-TOF. When compared to all conventional kinds (45 FA-TOF: 0.088 0.84, 90 FA-TOF: 0.203 0.72), the 90 FA-MinVER showed a similar signal profile to that of the traditional PSP and enhanced vessel-tissue contrast ratios (0.313 0.80). Furthermore, this noteworthy approach achieved a significantly reduced total acquisition time (5 min and 55 s) with a short repeat-to-time (28 ms), indicating that at 7 T TOF-MRA, the 90 FA-MinVER could be used by default to suppress venous signals regardless of individual human-dependent physiological effects and the specific absorption ratio constraint, as well as with the rapid TOF-MRA imaging. Finally, its use could aid in the early detection of modest microvascular alterations and act as crucial biomarkers in a variety of vascular disorders.


Author(S) Details


Sangwoo Kim
Department of Radiological Science, Daewon University College, 316, Daehak-ro, Jecheon-si, Chungcheongbuk-do, Republic of Korea.

Chulhyun Lee
Center for Research Equipment, Korea Basic Science Institute, 162, Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea.

View Book:- https://stm.bookpi.org/IDMMR-V8/article/view/5820

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