Friday, 27 May 2022

Determining the Effects of Methanolic Extracts of Quisqualis indica on Passive Smoking Induced Hyperlipidemia in Rats| Chapter 1 | Challenges and Advances in Pharmaceutical Research Vol.3

The hypolipidemic effect of methanolic and aqueous extracts of aerial portions of Quisqualis indica (QI), mostly flowers, on passive smoking (PS) induced hyperlipidemia in rats will be compared in this study. Hyperlipidemia was generated by passive smoking in a closed room with one burning cigarette inside. After treatment with the reagent contained in the auto span diagnostic kit, the hypolipidemic activity was assessed by detecting the amount of blood serum in UV at 505 nm. A dosage of Methanolic and aqueous extracts of QI was generated using distilled water, i.e. 100 mg/kg p.o. At varying concentrations and dosages, both QI extracts significantly reduce the hazardous lipid layer in blood serum. This indicates that the plant possesses hypolipidemic properties. It significantly reduces LDL, VLDL, cholesterol, triglycerides, and elevates HDL levels in blood serum, which might be due to the plants' antioxidants suppressing lipid peroxidation. Our findings suggest that methanolic plant extracts are superior than aqueous extracts in terms of reducing harmful lipids and restoring lipid metabolism abnormalities in hyperlipidemic patients.

Author(s) Details:

Jyoti Sahu,
Bharat Institute of Technology, Ibrahimpatnam and Siddhi Vinayak Institute of Technology, Bilaspur, Chhattisgarh, India.

Pushpendra Kumar Patel,
Bharat Institute of Technology, Ibrahimpatnam and Siddhi Vinayak Institute of Technology, Bilaspur, Chhattisgarh, India.

Please see the link here: https://stm.bookpi.org/CAPRV-3/article/view/6941

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