Except in the case of familial adenomatous polyposis, fundic gland polyps (FGPs) are the most common stomach polyps and have long been regarded to be benign lesions with low malignant potential. FGPs, on the other hand, have become more common in recent years, coinciding with the extensive and regular use of proton pump inhibitors (PPIs). So far, only a few cases of spontaneous FGPs with dysplasia or cancer (FGPD/CAs) have been reported. The goal of this research was to assess the clinical and endoscopic features of sporadic FGPD/CAs and propose a sporadic FGP therapy plan. The majority of patients with sporadic FGPD/CAs were middle-aged women who were not infected with Helicobacter pylori and were using PPIs (H. pylori). The majority of sporadic FGPD/CAs were sessile and small, with a mean size of only a few millimetres. The tumour was 5.4 mm in diameter and was found in the stomach body. During magnification narrow-band imaging, the sporadic FGPs with malignancy revealed redness, abnormal surface structure, depression, or erosion, and irregular microvessels on the lesion surface. Furthermore, sporadic FGPs are likely to progress slowly to malignancy, even if they have dysplasia. As a result, people with occasional FGPs don't need to go to the doctor as often. Histological study is essential whenever endoscopic findings different than traditional FGPs are discovered, regardless of their size. Because of the widespread and frequent use of PPIs and the decreasing H. pylori infection rate, the prevalence of FGPs is expected to grow in the future. It's unclear whether FGPD/CAs will rise at the same rate as FGPs. Nevertheless, the patterns of these lesions point to the need for greater research in the future.
Author(S) Details
Davis Kizhakkepeedika Rennis
Department of Pulmonary Medicine, Amala Institute of Medical Sciences, Amala Nagar, Thrissur, Kerala, India.
Easwaramangalath Venugopal Krishnakumar
Department of Pulmonary Medicine, Amala Institute of Medical Sciences, Amala Nagar, Thrissur, Kerala, India.
View Book:- https://stm.bookpi.org/NHMMR-V9/article/view/6896
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