The Predictive Value of Initial Arterial Blood Gas Variations in Pneumonia Patients with Type I/II Respiratory Failure | Chapter 02 | New Horizons in Medicine and Medical Research Vol. 9

 Early fluctuations in the individual arterial blood gas (ABG) parameters—pH, PaO2, PaCO2, and HCO3—and treatment success in pneumonia patients with respiratory failure have received little attention. If a statistically significant fluctuation in individual ABG readings could be utilised as an early, accurate predictor of treatment effectiveness, a patient with pneumonia who is in respiratory failure might be treated aggressively before a clinically evident downward shift occurs. Pneumonia can also cause respiratory failure by causing acute respiratory distress syndrome (ARDS), which is caused by a mix of infection and inflammation.

 

42 patients with clinical signs of pneumonia and baseline clinical data, as well as two arterial blood samples, were included in this prospective experiment. samples for ABG testing (one at baseline and another within 24 hours of the first). Based on the ABG findings, patients were classified as belonging to group 'A' with type I (hypoxemic) respiratory failure or group 'B' with type II (hypercapnic) respiratory failure. A binary logistic regression research was conducted. Individual ABG parameters in Group A had a significant positive connection with the treatment outcome: pH (p=0.034), HCO3- (p=0.034), PaO2 (p=0.035), PaCO2 (p=0.045), whereas pH (p=0.284), HCO3- (p=0.248), PaO2 (p=0.39), PaCO2 (p=0.240) had a non-significant positive association. The treatment failure rate in Group B was 40.91 percent, compared to 25 percent in Group A.

In pneumonia patients with type I respiratory disease, individual ABG levels can predict therapy outcome.

Author(S) Details

Davis Kizhakkepeedika Rennis
Department of Pulmonary Medicine, Amala Institute of Medical Sciences, Amala Nagar, Thrissur, Kerala, India.

Easwaramangalath Venugopal Krishnakumar
Department of Pulmonary Medicine, Amala Institute of Medical Sciences, Amala Nagar, Thrissur, Kerala, India.

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