Plants are crucial in the creation of medications, and the pharmaceutical industry relies heavily on natural ingredients to create new treatments. Curcumin is a natural compound found in the rhizomes of the plants Curcuma longa Linn, Cissus quadrangularis L., and Boerhaavia diffusa L. Curcumin is a natural compound found in the rhizomes of the plants Curcuma longa Linn, Cissus quadrangularis L., and Boerhaavia diffusa L. Curcumin is a natural compound found in the rhizomes of the plant.
The goal of this study is to see if the aqua-alcoholic extract of the herbal
mixture (Curcuma longa Linn + Cissus quadrangularis + Boerhaavia diffusa) has
any cytotoxic, antioxidant, thrombolytic, antiinflammatory, or antibacterial
activities.
Curcuma longa Linn, Cissus quadrangularis, and Boerhaavia diffusa were combined
to make an aqua-alcoholic extract. Phytochemical in-vitro studies using the CCB
mixture included cytotoxicity using the brine shrimp lethality assay,
antioxidant activity using the DPPH assay, anti-inflammatory activity using the
albumin denaturation assay, antimicrobial activity using the agar well
diffusion method against Staphylococcus aureus, Streptococcus mutans,
Escherichia coli, and Candida albicans, and thrombolytic activity using the clo.
The CCB mixture showed excellent cytotoxic activity at various concentrations
in a brine shrimp lethality assay, boosting antioxidant activity with DPPH
assay, increasing thrombolytic activity, anti-inflammatory activity, and
anti-microbial activity with increasing concentration, but the anti-microbial
activity was ineffective as positive controls.
In this in vitro study, the CCB combination showed significant cytotoxic,
antioxidant, thrombolytic, anti-inflammatory, and antibacterial activity. More
in vivo animal studies and human clinical trials are needed.
Author(s) Details:
Y. Dinesh,
Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
R. Abilasha,
Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
Pratibha Ramani,
Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
S. Rajesh Kumar,
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, India.
Please see the link here: https://stm.bookpi.org/CAPRV-3/article/view/6952
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