Aim: Although the polyherbal siddha formulation veppampoo
Mathirai is helpful at lowering blood pressure, it is unknown if it is safe.
The presence of heavy metals, aflatoxins, pesticide residue, and
microbiological count has yet to be determined. In the current investigation,
the parameters indicated above were assessed. The goal of this study was to
assess the safety parameters of Veppampoo Mathirai (heavy metals, aflatoxin,
pesticide residue, and microbiological profile), with the goal of determining
if the aforesaid parameters of VPM were within normal ranges as per AYUSH
standards.
Materials and Methods: The formulation was tested for its safety criteria at
Noble research solutions, kolathur, Chennai, accredited with ISO 9001: 2015,
according to AYUSH [Ayurveda, yoga, unani, siddha, naturopathy] Pharmacopoeial
laboratory for Indian medicine (PLIM) recommendations. An Atomic Absorption
Spectrometer (AAS) was used to evaluate heavy metals, and Thin Layer
Chromatography was used to analyse aflatoxins (TLC). The GC/MS technique was
used to assess pesticide residues, and the pour plate method was used to
determine microbiological counts.
The presence of heavy metals mercury, arsenic, lead, and cadmium was found to
be within the AYUSH Pharmacopoeial Laboratory for Indian Medicine Guidelines,
while Aflatoxin, pesticide residues, and microbes were not detected in the
sample, indicating that the formulation Veppampoo Mathirai (VPM) was
toxicity-free.
Conclusion: Heavy metal levels in VPM were below the permitted limit according
to AYUSH's PLIM guidelines. Aflatoxins and pesticide residues were absent from
the latest batch of VPM, as were microorganisms and specific diseases. As a
consequence, the current study demonstrates that the formulation is safe to use
in therapeutic settings.
Author(s) Details:
S. M. Chitra,
Department of Post Graduate Maruthuvam, Government Siddha Medical College,
Arumbakkam, Chennai-106, Tamil Nadu, India.
N. Anbu,
Department of Post Graduate Maruthuvam, Government Siddha Medical College,
Arumbakkam, Chennai-106, Tamil Nadu, India.
Please see the link here: https://stm.bookpi.org/CAPR-V2/article/view/6583
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