Background: Dupilumab is a biological medicine licenced for the treatment of moderate to severe atopic dermatitis (AD) that has been shown in clinical trials to have a strong therapeutic effect and ability to improve quality of life. The most prevalent side effects of dupilumab therapy were upper respiratory tract infection, headache, nasopharyngitis, injection-site reaction, herpes viral infection, and conjunctivitis. Punctal stenosis, also known as dupilumab-induced lacrimal duct obstruction, is a rare and poorly understood side effect of the medicine.
Aim: To present a
novel case of a young female with a history of Alzheimer's disease but no prior
major ocular signs who developed right eye punctal stenosis after one year of
Dupilumab medication.
Case Report: A
19-year-old female with a long history of Alzheimer's disease who developed
severe punctal stenosis and continued tearing from her right eye in the last
two months and was on dupilumab therapy for a year did not respond to
conservative ophthalmological drugs, but completely improved after
discontinuing dupilumab injection over a 6-month follow-up period.
Author(S) Details
Waqas S. Abdulwahhab
Department of Dermatology and Venereology, Al Qassimi Hospital, Sharjah, United Arab Emirates.
Fatima Ibrahim Alamiri
Department of Ophthalmology, Al Qassimi Hospital, Sharjah, United Arab Emirates.
Alaa S. Mehair
Department of Dermatology and Venereology, Al Qassimi Hospital, Sharjah, United Arab Emirates.
Fatma Abdulghaffar Qaderi
Department of Dermatology and Venereology, Al Qassimi Hospital, Sharjah, United Arab Emirates.
View Book:- https://stm.bookpi.org/NHMMR-V7/article/view/6662
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