Oroxylum indicum bark extracts are being studied to see if they have any hepatoprotective properties (L.) The hepatoprotective effect of petroleum ether, chloroform, methanolic, and aqueous extracts of O. indicum against carbon tetrachloride-induced liver injury in mice was investigated using silymarin as a control. The extracts' phytochemical content was determined.
SGOT, SGPT, and ALP (Serum Glutamate Oxaloacetate Transaminase, Serum Glutamate Pyruvate Transaminase, and Alkaline Phosphatase) enzyme activity were studied. In comparison to carbon tetrachloride therapy, alcoholi bark extracts of O. indicum demonstrated activity. The outcomes of this study back up the plant's traditional use as a hepatoprotective agent. In the statistical analysis, one-way measurement of variance (ANOVA) was utilized, followed by Dunnet's t-test. Significant P-values were defined as those less than 0.05.Author (s) Details
Mr. Bichitra NandaTripathy
Department of Pharmacognosy, Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India.
Prof.(Dr.) S. K. Panda
Department of Pharmacognosy, Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India.
S. Sahoo
Department of Pharmacognosy, Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India and University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bbsr-751004, Odisha, India.
S. K. Mishra
Department of Pharmacognosy, Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India and University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bbsr-751004, Odisha, India.
L. Nayak
Department of Pharmacognosy, Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India and University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bbsr-751004, Odisha, India.
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