Stimulating Mitochondrial Biogenesis through Exercise - a Viable Way to Prevent Severe Forms of COVID-19? | Chapter 2 | Technological Innovation in Pharmaceutical Research Vol. 3

 Exercise, particularly endurance exercise, can help prevent severe COVID-19 infection by stimulating mitochondrial biogenesis and improving their activity, with these organelles playing a critical role in the disease's etiology. Some drugs and supplements that stimulate mitochondrial biogenesis through exercise (6-hydroxy-2,5,7,8-tetramethylchromane-2- carboxylic acid (Trolox), 3 fatty acids, vitamin C, zinc, vitamin B12, folic acid, magnesium, MitoQ) and others that inhibit it (6-hydroxy-2,5,7,8-tetramethylchromane-2- carboxylic acid (Trolox), 3 fatty acids, vitamin C, zinc, vitamin B12 (acetylsalicylic acid, ibuprofen, acetaminophen). The medical theory that moderate-intensity exercise would stimulate muscle biogenesis would be put into practice. Reduce the chance of acquiring a severe form of COVID-19, and the number of deaths could drop by more than a third.

Author (s) Details

Hagiu Bogdan-Alexandru
Faculty of Physical Education and Sports, “Alexandru Ioan Cuza” University, Iasi, Romania.

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