This study aims to see if a potential cellular biological therapy could assist patients with hand osteoarthritis (OA) regulate their symptoms and recover hand function, allowing them to perform more activities of daily living and work more comfortably. OA of the hands is a tough illness to diagnose and treat. Analgesics, anti-inflammatory medicines, and hand exercises are commonly used to treat OA. In extreme situations, surgery is required, which may include joint repair, replacement, or fusion, depending on the affected location. We present the example of a 66-year-old woman who has suffered from symptomatic hand OA for six years, affecting her everyday activities and job as an aromatherapist. She had a good response to adipose-derived autologous expanded mesenchymal stem cell (MSC) therapy, which we performed under ultrasound guidance after a digital nerve block for the second through fifth distal interphalangeal joints on both sides. The improvements began one month after the stem cell implants, with the greatest effect occurring ten months after the therapy, which persisted for the rest of the patient's life. In comparison to the baseline x-ray, a fourteen-month follow-up x-ray demonstrated no radiological advancement of OA in the treated joints. She continued to appreciate the simple pleasures of daily life and employment. Despite the consistent response, she decided to take a booster dosage of MSC therapy to keep her function and prevent OA progression. This instance had good clinical and functional outcomes, with no further OA joint deterioration on x-rays, indicating a viable therapy for hand OA that no other existing medical treatment has been able to achieve thus far.
Author(S) Details
Hassan Mubark
Department of Rheumatology, Auckland Regenerative Clinic, Ormiston Specialist Centre, New Zealand.
View Book:- https://stm.bookpi.org/IDMMR-V3/article/view/5474
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