The study was aimed to evaluate the relationship between the iron deficiency anemia (IDA) and type
2 diabetes, to estimate the effect of the
IDA on the level of glucose and glycated hemoglobin (Hb1Ac)
and to assess the ameliorating effect of
IDA treatment on progression of diabetes and its
complications. This study included 125
male Fasting blood glucose (FBG), HbA1c, CBC, ferritin, iron,
and total iron binding capacity (TIBC)
were assayed. The HbA1c and FBG levels were significantly
higher in groups III and IV compared to
group I. The results revealed a significant decline in HbA1c
and FBG levels in group V compared to
group IV. Negative significant correlations were observed
between iron and ferritin with HbA1c and
FBG. Ferritin was the most reliable predictor of type 2
diabetes in patients with IDA. The best
cut off value for ferritin was 31.56 ng/ml. Low iron level has a
crucial effect on glycemic status by
increasing the level of FBG and HbA1c, IDA is strongly correlated
with type 2 diabetes and the iron
supplementation for diabetic patients with IDA ameliorates the
progression of diabetes and its complications.
Author (s)
Details
Department of Pharmacology and
Toxicology, College of Pharmacy, Qassim University, Qassim, Saudi Arabia and
Hormones Department, Medical Research Division, National Research Centre, Giza,
Egypt.
Rehab M. Elgharabawy
Department of Pharmacology and
Toxicology, College of Pharmacy, Qassim University, Qassim, Saudi Arabia and
Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University,
Egypt.
Amal H. Al-Najjar
Drug and Poison Information Specialist,
Pharmacy Services, Security Forces Hospital, Riyadh, Saudi Arabia.
Monerh H. Al-Abdullatif
College of Pharmacy, Qassim
University, Qassim, Saudi Arabia.
Mona A. Al-Abdullatif
College of Pharmacy, Qassim
University, Qassim, Saudi Arabia.
Turki A. Al-Mogbel
Buraydah Diabetes Center, King
Fahad Specialist Hospital, Saudi Arabia.
View Book
:- https://bp.bookpi.org/index.php/bpi/catalog/book/239
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