The present study evaluates the synthesis
of water-insoluble compounds into tablets with a sustained release matrix and
the effect of aloe vera gel powder on the dissolution and other physical
properties of tablets with the SR matrix. As a polymer, HPMC and ethyl
cellulose were used and various The
concentration of aloe vera gel powder used as the enhancer of dissolution. By
direct compression process, sustained release matrix tablets were formulated
and subjected to various quality control studies as per The official Guidelines for Pharmacopoeia. The
tablet formulation that has been produced complies with the monograph. The
findings suggest that the dissolution of curcumin is stimulated by aloe vera.
Kinetics of dissolution indicate that all the formulation followed the model of
Korsemayer Peppas by anomalous diffusion
Mechanism. To conclude, the dissolution enhancer of aloe vera gel powder
can be used to increase the drug absorption of water-insoluble products.
Author (s) Details
Dr. Habibur Rahman
Faculty of Pharmaceutical Sciences, UCSI University, Malaysia and PSG
College of Pharmacy, Coimbatore, Tamil Nadu, India.
Dr. Telny Thomas Chungath
Chemists College of Pharmaceutical Sciences and Research, Ernakulum, Kerala,
India.
View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/272
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