The aim of this study was to evaluate the efficacy of
the ivermectin tablet administered orally for
Sarcoptes scabiei treatment in naturally
infested dogs. Fourteen dogs (7 males and 7 females)
mongrel dogs, one to five years-old presenting positive
skin scrapings for S. scabiei mites,
distributed
into two groups with equal proportions of both sexes,
containing seven animals per group were used
in this study. All animals were treated every 7 days,
totalizing four treatments in each dog (days 0, +7,
+14 and +21). The Group I received ivermectin tablet at
a dose of 0.2 mg/kg and the positive control
group (Group II) received a commercial product based on
ivermectin tablet at the same dose of Group
I. Skin scrapings, clinical and laboratorial parameters
analysis were performed during the
experimental period. Clinically, there were no
significant differences between the two groups
evaluated prior and after treatments. Negative skin
scrapings were observed in both groups from day
D+14, remaining negative until the end of the
experimental period. The initial skin lesions observed in
clinical evaluation regressed from day D+14, and
clinical improvement was evident in both groups.
The ivermectin tablet (Ivermectan Pet®,
UCBVET Saúde Animal) administered orally was effective to
treat S. scabiei infestation
in naturally infested dogs.
Author (s) Details
Gisele
Maria de Andrade
Department of Research & Development
(Pharmacotechnics, Physical-Chemical and Technical), UCBVET Saúde Animal. Praça
Dr. Joaquim Batista, 150, Centro, Jaboticabal, SP 14870-090, Brazil.
Moacir Marchiori Filho
Department of Research & Development (Pharmacotechnics, Physical-Chemical
and Technical), UCBVET Saúde Animal. Praça Dr. Joaquim Batista, 150, Centro,
Jaboticabal, SP 14870-090, Brazil.
Marcelo Brunini
UCBVET Saúde Animal. Praça Dr. Joaquim Batista, 150, Centro, Jaboticabal,
SP 14870-090, Brazil.
Armando Leonelo Neto
Department of Research & Development (Pharmacotechnics,
Physical-Chemical and Technical), UCBVET Saúde Animal. Praça Dr. Joaquim
Batista, 150, Centro, Jaboticabal, SP 14870-090, Brazil.
Raquel A. Ré
Department of Research & Development (Pharmacotechnics,
Physical-Chemical and Technical), UCBVET Saúde Animal. Praça Dr. Joaquim
Batista, 150, Centro, Jaboticabal, SP 14870-090, Brazil.
Alice T. S. de Matos
Department of Research & Development (Pharmacotechnics,
Physical-Chemical and Technical), UCBVET Saúde Animal. Praça Dr. Joaquim
Batista, 150, Centro, Jaboticabal, SP 14870-090, Brazil.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/267
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