Monday, 17 April 2023

Optimization Extraction Conditions of Some Flavonoids from Elsholtzia ciliata Leaves by Response Surface Method | Chapter 4 | Current Overview on Pharmaceutical Science Vol. 9

 In this study, the distillation conditions of various flavonoid compounds from Elsholtzia ciliata leaves were optimized for one response surface means (RSM). The experiment was arranged in accordance with the Box - Behnken design accompanying 15 experiments and was built established an optimized process for the ancestry of ethyl gallate (Y1), rutin (Y2), apigenin (Y3), and quercetin (Y4) with 3 determinants of extraction hotness (X1), extraction period (X2) and pressure (X3). The conditions for optimizing the ancestry process to obtain the best content of some flavonoid compounds were at 57O C, 54 notes of meeting, and 100 bar pressure. The experimental principles at the optimal limits of ethyl gallate, rutin, apigenin, and quercetin are 97.65 ± 0.32 mg/100g, 35.50 ± 0.25 mg/100g, 17.62 ± 0.15 mg/100g, and 27.66 ± 0.20 mg/100g, respectively.

Author(s) Details:

Truong Nhan Ngu,
Department of Natural Sciences and Technology, Tay Nguyen University, 567 Le Duan, Buon Ma Thuot, Dak Lak 630000, Vietnam.

Dam Thi Bich Hanh,
Department of Science and Technology, Tay Nguyen University, 567 Le Duan Str., Buon Ma Thuot, Dak Lak province, 630000, Vietnam.

Trinh Ngoc Thao Vy,
Department of Medicine and Pharmacy, Tay Nguyen University, 567 Le Duan Str., Buon Ma Thuot, Dak Lak province, 630000, Vietnam.

Van-Tinh Nguyen,
Applied Biomedical Research Institute, Buon Ma Thuot Medical University, 298 Ha Huy Tap Street, Buon Ma Thuot, Dak Lak, 630000, Vietnam.

Phi-Hung Nguyen,
Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi 122100, Vietnam.

Manh Hung Tran,
School of Medicine & Pharmacy, The University of Danang, Hoa Quy, Ngu Hanh Son, Da Nang City 550000, Vietnam.

Dao-Cuong To,
Phenikaa University Nano Institute (PHENA), Phenikaa University, Yen Nghia, Ha Dong District, Hanoi 12116, Vietnam.


Please see the link here: https://stm.bookpi.org/COPS-V9/article/view/10169



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