Modern Techniques to Study Biokinetics of Nanoobjects in Living Organisms | Chapter 8 | Research Highlights in Science and Technology Vol. 1

 Strictly, Nanosafety is a field of Biomedicine. However, the plurality of the techniques grown and used for research in Nanosafety is interdisciplinary. Investigation of biokinetics of nanoobjects is an main arm of Nanosafety, which admits to estimate the toxicological load in the tissues of an unprotected organism and anticipate healing effect of the medicine. The present episode reviews various new methods to study the biokinetics of nanoobjects in living organisms. Common patterns of the biokinetics of exogenic wealth in a living organism and the big standard of a toxicological experiment are presented. A ample and inclusive presentation of Atomic Emission Spectrometry; Mass Spectrometry; X-ray Fluorescence Spectroscopy and Nuclear Physical Techniques to a degree Neutron Activation Analysis, Radiotracer Technique, In situ Neutron Activation Analysis; Microscopy and the article of their application or in general area of research are given. General mechanics approvals for the experiment planning are planned. The hypothetical approach to study nanoobject biokinetics based on the PBPK-displaying is thought-out. Examples of original studies on the biokinetics of TiO2 and Ag nanoparticles implemented accompanying the use of the deliberate techniques are bestowed. Authors attempted to share their own occurrence of research engaged of Nanosafety.

Author(s) Details:

A. A. Antsiferova,
National Research Center “Kurchatov Institute”, 1, Akademika Kurchatova sq., 123182 Moscow, Russia and Moscow Institute of Physics and Technologies, 9, Institutskii Lane, Moscow Region, 141700 Dolgoprudny, Russia.

P. K. Kashkarov,
National Research Center “Kurchatov Institute”, 1, Akademika Kurchatova sq., 123182 Moscow, Russia, Moscow Institute of Physics and Technologies, 9, Institutskii Lane, Moscow Region, 141700 Dolgoprudny, Russia and Department of Physics, Lomonosov Moscow State University, 1, GSP-1, Leninskiye Gory, 119991 Moscow, Russia.

Please see the link here: https://stm.bookpi.org/RHST-V1/article/view/10417