Periodontal diseases continue to be one of the most common chronic infectious and inflammatory diseases in the world. Pathogenic mechanisms acting in periodontal diseases contain two major arms: the microbial component and the host response. Knowledge on both aspects has been increasing tremendously during the last two decades. Indeed, the progress in knowledge and the available evidence have led European Federation of Periodontology and American Academy of Periodontology to combine power and build up a new classification system for periodontal diseases in 2017 after 18 years passed since the 1999 Classification.
Periodontology is one of the most glamorous fields of dentistry with dozens of exciting papers, which open up completely novel pathways of research. “The more we understand the scenario the more complex it becomes.” This is quite true for periodontology. However, this complexity not only attracts even more scientists to work in this field but also stimulates building new bridges between various disciplines of dentistry and medicine to make the story clear.
Development of chair-side diagnostic tests for determining the presence or absence of periodontal disease and activity is still a challenge in periodontology. The use of biofluid samples such as gingival crevicular fluid, whole saliva, and serum as a means of evaluating host-derived products, as well as exogenous components has a great potential for diagnosis and monitorisation of periodontal diseases. Having more precise and early diagnostic tools may enable early intervention and help to develop individually tailored treatment modalities. We are not there, yet, but shall expect to arrive soon. The technological developments in laboratory methods and the closer collaboration with different branches of medicine bring great hope for the future.
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health.
Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.Author(s) Details:
Neelam Das,
Department of Periodontology, Rama Dental College, Hospital & Research Centre, Kanpur, Uttar Pradesh - 208024, India.
Please see the link here: https://stm.bookpi.org/CAMBMPHDCP/article/view/10228
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