Wednesday 26 April 2023

The Ventricular-subventricular Zone, a Source of Myelinating Oligodendrocytes | Chapter 4 | Research Highlights in Disease and Health Research Vol. 6

 In the postnatal mind, the ventricular-subventricular zone (V-SVZ) is a well-known neurogenic domain that contains affecting animate nerve organs stem cells. These multipotential progenitors generate new neurons that move via the rostral transient stream to reach the olfactory bulb, place they differentiate into functional interneurons that help odor-bias tasks. Additionally, the neural stem cells of V-SVZ are still a source of oligodendrocyte parent cells. These progenitors migrate and occupy the neighboring corpus callosum, place they contribute to physical myelin preservation and help in remyelination after silver matter lesions. However, the production of these forerunners is limited, but the oligodendroglia generation maybe triggered by stimulating V-SVZ progenitors by way of the epidermal growth determinant receptor or some synthetic agonists, that are currently feasible for clinical purposes.

Author(s) Details:

Oscar Gonzalez-Morales,
Departamento de Bioingeniería, Escuela de Ingeniería y Ciencias,Tecnologico de Monterrey, Zapopan-45201, Mexico.

Rocío E. Gonzalez-Castañeda,
Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara-44340, México.

Oscar Gonzalez-Perez,
Facultad de Psicología, Laboratorio de Neurociencias, Universidad de Colima, Colima-28040, México.

Please see the link here: https://stm.bookpi.org/RHDHR-V6/article/view/10282


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