Thursday, 20 April 2023

In vitro Assessment of Free Radicals and Trace Metal Species in Salivary Secretions: A Rapid Detection Method for the Prognosis of Oral Precancerous Cancerous Conditions | Chapter 3 | Cutting Edge Research in Biology Vol. 6

 In this In vitro study, judgment of biochemical diagnostic gravestones like prooxidants, free radicals, total protein content and trace elements has existed carried out. Significant advancement in the level of lipid peroxides (p<0.001) in Oral Squamous Cell Carcinoma (OSCC) was found when distinguished to Oral Sub Mucous Fibrosis (OSMF) patients. Conjugated dienes (p<0.001) were erect to be raised in OSMF compared to OSCC subjects. There were increased levels of hydroxyl and hydrogen peroxides radicals (p<0.001) in OSMF compared to OSCC victims. An elevated level of trace pieces (p<0.001 & p<0.05) was found in OSMF than OSCC subjects. High level of zinc & iron (p<0.001) were in the direction of OSCC patients. Total protein content and trace aspects alone were in the direction of normal active individuals. No perceptible amount of prooxidants and free radicals were observed in sane healthy things. This shows that the above limits may be secondhand as good biochemical diagnostic gravestone for the detection of spoken cancer at early stages of tumor development.

Author(s) Details:

M. Balasubramanian,
Department of Biotechnology, Vivekanandha Arts and Science College for Women, Veerachipalayam, Sankagiri West, Salem District, Tamilnadu State, India.

S. Anandhi,
Department of Biotechnology, Vivekanandha Arts and Science College for Women, Veerachipalayam, Sankagiri West, Salem District, Tamilnadu State, India.

Please see the link here: https://stm.bookpi.org/CERB-V6/article/view/10218

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