This division aims to compare the hyperglycemic control of M. oleifera leaves liquid extract and Glibenclamide tablet in alloxan monohydrate inferred diabetic rats.In this experiment, Twenty-four female Wister albino rats, fashioned diabetic using alloxan monohydrate, taken either M. oleifera extract, glibenclamide or distilled water were delivered intragastric.The verdicts showed that Rats that taken distilled water had a mean abstaining blood sugar of 329.3+44.9mg/dl at first, which raised to 448.0+189.9mg/dl on day 14, all the rats were dead by era 21. The rats that received M. oleifera had glucose 443.4+134.7mg/dl at the beginning, discontinued to 166.5+162.79mg/dl by day 14, and to 88.7+41.0 mg/dl by epoch 28. Rats that received glibenclamide had blood sugar 517.6+139.3mg/dl at first, dropped to 209.0+201.9mg/dl on day14, and to 89.7+42.85mg/dl eventually 28. The blood sugar levels in the M.oleifera and glibenclamide groups restored to normal by era 21 and remained inside the normal range as far as the experiment was completed eventually 28. Based on the findings concerning this study, it can be concluded that Moringa oleifera leaves liquid extract has similar pattern to glibenclamide pellet in causing hypoglycemia to alloxan monohydrate persuaded diabetic rats.
Author(s) Details:
Josephine N. Kasolo,
Department of Physiology, Makerere College of
Health Sciences, Uganda.
Agnes
Namaganda,
Department
of Physiology, Makerere College of Health Sciences, Uganda.
Joshua Nfambi,
Department of Physiology, Makerere College of Health Sciences, Uganda.
Ivan Kimuli,
Department of Physiology, Makerere College of Health Sciences, Uganda.
Haruna
Muwonge,
Department of Physiology, Makerere College of
Health Sciences, Uganda.
Allan
Lugaajju,
Department
of Physiology, Makerere College of Health Sciences, Uganda.
Isaac Okullo,
Department of Dental Surgery, Makerere College of Health Sciences,
Uganda.
Please see the link here: https://stm.bookpi.org/COPS-V9/article/view/10168
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