This present study was acted to evaluate an active alternative over present medication against parasitical infection cruel. Vitex negundo (Family: Verbenaceae) is a useful drugs in Ayurveda and widely used by the ancestral people. The phytochemical protect of Vitex negundo (leaves &bark) extract showed the occupancy of phenolics and flavonoids, those are responsible for antiviral, uncontaminated, anti hypersensitive, antihypertensive, antiarrythmic, hepatoprotective, anti-angering effects in animals [1,2,3]. Our present studies was done on Pheretima posthuma model (Indian earthworm)to discover antiprotozoal effect).Three concentrations 10,20 & 40 mg/ml extracts of V.negundo (leaves and bark) were used for this study that involved the determination momentary of paralysis (vermifuge) and occasion of death (vermicidal endeavor) of the worms, where the aggregation of 40 mg/ml showed a meaningful anthelmintic activity. Observations were corresponding with the standard drug at aggregation of 10mg/ml.of piperizine citrate. Although more chemical in addition to clinical studies are necessary to exhibits determined its capability to become of main pharmacological interest.
Author(s) Details:
Sibaram Paria,
School
of Pharmacy, The Neotia University, Sarisa, West Bengal 743368, India.
Subhasish
Mondal,
School
of Pharmacy, The Neotia University, Sarisa, West Bengal 743368, India.
Please see the link here: https://stm.bookpi.org/COPS-V4/article/view/9305
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