The epidemiological, dispassionate, pathophysiological, and immunogenetic characterization of autoimmune and autoinflammatory ailments as a whole would provide appropriate clinical and paraclinical clues, healing targets, and birth control method approaches in common for some autoimmune and autoinflammatory ailments. Panorama studies of autoimmune and auto-instigative diseases are still very little completed activity in Africa and particularly in Mali. Here, first of all, the objective concerning this observational cross-localized and descriptive study accompanying retrospective data group for 15 years search out describe the epidemiological and dispassionate profile of all autoimmune and auto-angering diseases in the area of internal cure at the University Hospital Center of the Point G. Globally, 6,383 patients were hospitalized in within medicine at the University Hospital Center of the Point G, of that 317 patients bestowed with autoimmune and/or auto-angering disease accompanying an average annual hospital conscription rate of 21 ± 7.87 cases per year. Out of the 317 medical records that join our inclusion tests,there were 07 cases of friendship between autoimmune disease and autoinflammatory ailment, totaling 14 instances of two together autoimmune and autoinflammatory disorders. A total of 331 autoimmune diseases and/or automobile-inflammatory diseases were calm, i.e. a commonness of 5.19%, including 291 cases of autoimmune ailments (221 cases of organ-specific autoimmune ailments and 70 cases of systemic autoimmune ailments) and 40 cases of autoinflammatory diseases (no case of monogenic forms, 08 cases of “fundamental” polygenic forms and 32 cases of “organ-distinguishing” polygenic forms). Organ-specific autoimmune diseases were governed by type 1 diabetes (141 cases), Graves’ disease (48 cases) and fundamental autoimmune diseases by integral lupus erythematosus (43 cases), rheumatoid arthritis (16 cases). Among the auto-inflammatory ailments, the “systemic” polygenic forms were ruled by Horton's disease (02 cases) and the “means-specific” polygenic forms by gout (16 cases), ulcerative colitis (08 cases). According to our verdicts, autoimmune and autoinflammatory diseases are typified in internal cure by their frequent occurrence in women, rather between the ages of 25 and 44, accompanying a very disparate classification. We also found that tool-specific autoimmune afflictions outnumbered systemic one, and "organ-specific" polygenic autoinflammatory afflictions outnumbered "systemic" one.
Author(s) Details:
Keïta Kaly,
Department of Internal Medicine at the
University Hospital Center of the Point G, Bamako, Mali.
Soukho
Assétou Kaya,
Department
of Internal Medicine at the University Hospital Center of the Point G, Bamako,
Mali and Faculty of Medicine and Odontostomatology (FMOS), University of
Sciences, Techniques and Technologies of Bamako (USSTB), Mali.
Sy Djibril,
Department of Internal Medicine at the University Hospital Center of the
Point G, Bamako, Mali and Faculty of Medicine and Odontostomatology (FMOS),
University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.
Traoré Djénébou,
Department of Internal Medicine at the University Hospital Center of the
Point G, Bamako, Mali and Faculty of Medicine and Odontostomatology (FMOS),
University of Sciences, Techniques and Technologies of Bamako (USSTB), Mali.
Cissé
Idrissa Ahmadou,
Faculty of Medicine and Odontostomatology
(FMOS), University of Sciences, Techniques and Technologies of Bamako (USSTB),
Mali and Department of Rheumatology at the University Hospital Center of the
Point G, Bamako, Mali.
Diakité
Mahamadou,
Faculty
of Medicine and Odontostomatology (FMOS), University of Sciences, Techniques
and Technologies of Bamako (USSTB), Mali, University of Clinical Research Center
(UCRC) at the University Hospital Center of the Point G, Bamako, Mali and
Malaria Research and Training Center (MRTC), University of Sciences, Techniques
and Technologies of Bamako (USSTB), Mali.
Dembélé Mamadou,
Faculty of Medicine, Kankou Moussa University (UKM), Bamako, Mali.
Traoré Abdel Kader,
Faculty of Medicine, Kankou Moussa University (UKM), Bamako, Mali.
Traoré Hamar Alassane,
Faculty of Medicine, Kankou Moussa University (UKM), Bamako, Mali.
Please see the link here: https://stm.bookpi.org/RHDHR-V2/article/view/9653
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