This review aims to review the latest evidence concerning the current and future treatment of diabetic cardiac unrestrained politically neuropathy (CAN). Search strategy. Scopus, Science Direct (from Elsevier), and PubMed containing Medline databases were searched. In order to recognize research results that could not take place during the connected to the internet search, a manual search of the bibliography of disclosures was used. Lifestyle changes and exhaustive glycemic control may help for fear that the onset or progression of CAN. The pathogenetic administration of CAN entails equalized hypocaloric diet and physical activity; growth of glycemic control; treatment of dyslipoproteinemia; discipline of metabolic abnormalities in myocardium; stop and treatment of loss of consciousness fromblockage in vein or artery; use of aldose reductase inhibitors; dihomo-Y-linolenic acid (DGLA), acetyl-L carnitine, antioxidants, first of all α-lipoic acid (α-LA), use of ω-3 and ω-6 polyunsaturated greasy acids (ω-3 and ω-6 PUFAs), vasodilators, fat-soluble source of nourishment B1, aminoguanidine; substitutive medicine of growth determinants, in severe cases-situation of orthostatic hypotension. Promising treatments contain studying and utilizing substances that correct blood flow through the vasa vasorum, in the way that prostacyclin analogues, thromboxane A2 blockers, and medications that help to restore and/or normalise Na+, K+-ATPase (phosphodiesterase inhibitor), ω-LA, DGLA, (ω-3 PUFAs, and the concurrent prescription of (α-LA), (ω-3 PUFA and DGLA.
Author(s) Details:
Victoria Serhiyenko,
Department of Endocrinology, Danylo Halytsky
Lviv National Medical University, Ukraine.
Marta
Hotsko,
Department
of Endocrinology, Danylo Halytsky Lviv National Medical University, Ukraine.
Ludmila Serhiyenko,
Department of Medical Biology and Genetics, Danylo Halytsky Lviv National
Medical University, Ukraine.
Alexandr Serhiyenko,
Department of Endocrinology, Danylo Halytsky Lviv National Medical
University, Ukraine.
Please see the link here: https://stm.bookpi.org/RDMMS-V1/article/view/9622
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