Assessment of Plasma Cell Leukemia Occurring in Post-Covid-19 Associated with a Paraneoplastic Limbic Encephalitis | Chapter 10 | Perspective of Recent Advances in Medical Research Vol. 11

 Patients accompanying chronic lymphocytic leukemia show a high-risk population for COVID-19. Moreover, the answer to SARS-CoV-2 vaccination is frequently absent or inadequate. A 73-period-old corpulent individual was diagnosed accompanying an acute COVID-19 infection. The patient’s condition enhanced, but six months later a new deterioration emanated. Following the appearance of pancytopenia, plasmacytosis involved the minor blood (35%), in addition to the bone essence (31%), disclosing an osteoclastic pattern. An encephalitis that prevailed at that stage was of the limbic type. It presented anti-GABA B-antibodies. Therefore, the condition being neither an contamination, nor a metabolic disorder, nor a vascular lesion, is most consistent accompanying an autoimmune reaction. The dispassionate features were consistent accompanying a plasma container myeloma, associated with a paraneoplastic disease. Despite some criteria not being join, the POEMS syndrome was the chosen diagnosis. It was kept awake by a fluid accumulation that suffused both pleural gutters and the district around an enlarged hate. This POEMS case had a connection to COVID-19 through two together the initial acute scene and a potential subacute COVID-19 pulmonary disorder that was determined by meaningful radiologic ground glass changes. In this case, apart from having plasma container leukaemia, the patient also knowledgeable hypoxemic respiratory insufficiency and withered from respiratory loss. As a result, we have described a POEMS condition that was caused by plasma container leukaemia and complicated by pulmonary COVID-19, likely with long COVID features.

Author(s) Details:

Ory Rouvio,
Department of Hematology, Soroka University Medical Center, FOHS, Ben Gurion University of the Negev, Beer Sheva, Israel and Internal Medicine A, Soroka University Medical Center, FOHS, Ben Gurion University of the Negev, Beer Sheva, Israel.

Itai Levi,
Internal Medicine A, Soroka University Medical Center, FOHS, Ben Gurion University of the Negev, Beer Sheva, Israel.

Daniel Benharroch,
Department of Pathology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

Please see the link here: https://stm.bookpi.org/PRAMR-V11/article/view/9517