An Investigator Led Clinical Trial in Practice Showing the Efficacy of Tamsulosin and Silodosin as Medical Expulsive Therapy in the Management of Distal Ureteral Stones: A Case Study in Urology | Chapter 10 | Perspective of Recent Advances in Medical Research Vol. 12

 Alpha blockers are being usually used as something which incites activity in the medical management for the banishing of ureteral stones. The present randomized study aims to judge the efficacy of Tamsulosin and Silodosin as healing therapy in the administration of symptomatic distal ureteral gravels.Methods: In this randomized control study the 120 patients registered were allotted to three groups. Patients camp 1 received pellet Tamsulosin 0.4 mg/day, group 2 taken tablet Silodosin 8mg/epoch and group 3 served as the control group. Parameters famous were the blood pressure, pebble position (% of expulsion in each group), antagonistic events famous and number of hospital visits. All cases were followed up newspaper for a period of 28 days.Results: Study demonstrated that both Tamsulosin (80% gain) and Silodosin (85 %success rate) are evenly efficacious when distinguished to the control group. Group 1 and Group 2 required less of pain murderers and also had less frequent emergency room admissions due to agonizing episodes as distinguished to the control group. Usual adverse response seen accompanying alpha blockers like orthostatic hypotension and reverting ejaculation were stated by few subjects in the test groups.Conclusions: Both the drugs give the impression effective in the health management of distal ureteral stones.ButTamsulosin scores over Silodosin as it’s well allowed and with good rock expulsion rates.

Author(s) Details:

A. S. Albert,
Caritas Hospital, Caritas Hospital Rd, Kottayam, Thellakom, Kerala-686630, India.

Santosh R. Pillai,
Department of Pharmacology, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala-689101, India.

Anila Mary,
Primary Health Centre, Mylom, Kollam District, Kerala, India.

Rajeev Aravindakshan,
Department of Community and Family Medicine, Medical College Building, All India Institute of Medical Sciences, Room No. 302, Mangalagiri, Guntur, Andrapradesh-522503, India.

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