Retrospective Analysis of Urinary Tract Infection in the Pediatric Population at a Tertiary Care Centre | Chapter 13 | Research Highlights in Disease and Health Research Vol. 2Retrospective Analysis of Urinary Tract Infection in the Pediatric Population at a Tertiary Care Centre | Chapter 13 | Research Highlights in Disease and Health Research Vol. 2

 Background: Urinary area infection (UTI) is among ultimate common contaminations occurring during period of being young. It is caused by both grandam-negative and gram-beneficial bacteria and Escherichia coli is the most average causative agent.Methods: Data of all pediatric inmates in the age group of 6 months to 18 years accompanying urinary tract contamination were taken for analysis. Urine samples were calm and cultured on the cystine lactose electrolyte- inadequate medium. The presence of microorganisms was identified using biochemicals, and the antimicrobial test was acted using the Kirby-Bauer test or the VITEK 2 compact system (bioMérieux, Inc., France).Results: The predominance of UTI was 23.5%. In total, 614 specimens proven positive with important bacteriuria. The male-to-female ratio was 1:2.3. Approximately 54% patients bestowed with urinary syndromes alone. Culture positivity was considerably associated with pyuria (p < 0.0001). E. coli (334/614) was the most universal isolate, attended by Enterococcus spp. (92/614). Colistin, polymyxin B, fosfomycin, nitrofurantoin, netilmicin, and amikacin were extremely good acting antimicrobials. Meanwhile, ampicillin, cefotaxime, ceftriaxone, and norfloxacin were well resistant to gram-negative microorganisms. Multidrug- resistant bacteria and lengthened-spectrum being tested-lactamase-producing bacteria were in the direction of 47% and 44.1% of cases, respectively. Vancomycin, linezolid, teicoplanin, and nitrofurantoin were highly productive against gram-certain bacteria. Furthermore, norfloxacin, trimethoprim/sulfamethoxazole, ciprofloxacin, and tetracycline were very resistant to gram-helpful bacteria. Of the 92, 42 Enterococcus spp. were opposing to high-dose gentamicin.Conclusion: Nitrofurantoin and amikacin maybe used as empirical remedy for gram-negative and grandam- positive bacteria. Because fighting to various commonly secondhand antibiotics is found expected increasing, situation must be guided by antibiotic susceptibleness reports.

Author(s) Details:

Naz Perween,
Department of Microbiology, Post Graduate Institute of Child Health, Noida, India.

Sumit Rai,
Department of Microbiology, All India Institute of Medical Sciences, Mangalagiri, Mangalagiri, India.

Sumi Nandwani,
Department of Microbiology, Post Graduate Institute of Child Health, Noida, India.

Shyam Kishor Kumar,
Department of Microbiology, All India Institute of Medical Sciences, Mangalagiri, Mangalagiri, India.

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