The goal of this study was to describe one of the difficulties in diagnosing liver abnormalities in the context of cancer diagnosis, as well as the impact on patient management. In computed tomography (CT) and magnetic resonance imaging (MRI), hepatic steatosis is a common result (MRI). Chemotherapy increases the risk of fatty liver infiltration as well as hemosiderosis. Multiple focal nodular fatty infiltration with unusual appearance and behaviour is uncommon, and when it is associated with a history of malignancy and/or infection, it presents a dilemma in which a confident diagnosis may not be rendered by MRI, necessitating a diagnostic biopsy to resolve the uncertainty in diagnosis. We discuss a case of a patient who got a fungal lung infection while receiving salvage chemotherapy for a second relapse of acute myelogenous leukaemia (AML). On MRI, there were progressive target-shaped focal liver lesions with distinctive fatty signal intensity, as well as evidence of hemosiderosis of the liver parenchyma. To achieve the final diagnosis of focal fatty infiltration and rule out the differential diagnoses of liver abscesses and leukaemia infiltration, target and non-target liver trucut biopsies were required.
Author(S) Details
M. El Khaldi
Department of Diagnostic Radiology, King Hussein Cancer Center, Jordan.
M. Al Hussaini
Department of Pathology, King Hussein Cancer Center, Jordan.
M. Abu Shattal
Department of Diagnostic Radiology, King Hussein Cancer Center, Jordan.
H. Abu Jazar
Bone Marrow Transplantation and Medical Oncology Departments, King Hussein Cancer Center, Jordan.
M. Swaidan
Department of Diagnostic Radiology, King Hussein Cancer Center, Jordan.
View Book:- https://stm.bookpi.org/IDMMR-V4/article/view/5544
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