Sunday 23 January 2022

Bioactivity of Anethum graveolens – An in silico Approach | Chapter 6 | New Visions in Biological Science Vol. 8

 The herb Anethum graveolens produces essential oil and is commonly used as a flavouring ingredient. Polyphenols, which have antioxidant and carminative qualities, are found in it. This study uses phytochemical screening to assess the presence of terpenoids, flavonoids, and tannins, among other things. Lipid peroxidation is common in food items, and synthetic antioxidants like butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT), both carcinogenic in nature, are employed to counteract it. As a result, demand for antioxidants produced from plants is increasing. The goal of this work is to predict the antioxidant and bioactivity of Limonene, Carvone, - Phellandrene, Dillapiol, Geraniol, and p-Cymene in Anethum graveolens, a plant rich in antioxidants. For in silico research, the PASS prediction tool was employed, and bioactive molecules with Pa> 0.7 were predicted. The bioactivity score for these substances is determined, and Lipinski's rule of 5 analysis is used to discuss their potential medical relevance. According to the study's findings, all of the chemicals have bioactivity and could be used in the health care, cosmetics, and food and beverage industries as possible antioxidants.


Author(S) Details

J. V. Madhuri
Geethanjali College of Engineering and Technology, Cheeryal, Hyderabad, India.

View Book:- https://stm.bookpi.org/NVBS-V8/article/view/5380

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