Thursday, 3 March 2022

A Descriptive Study on Antimicrobial Drugs Usage in a Tertiary Care Hospital| Chapter 12 | Current Aspects in Pharmaceutical Research and Development Vol.9

 Background: The emergence of resistant organisms is disturbingly prevalent all over the world. Antimicrobials are one of the most often given medicine classes in hospitals. Irrational and inappropriate antimicrobial prescriptions, in addition to poor patient compliance, are a substantial factor to the development of drug resistance. It is vital to increase physician and patient awareness of antibiotic resistance. In order to battle resistant organisms, sometimes known as super bugs, physicians and surgeons should be encouraged to participate in infectious disease control training programmes on a regular basis.

Objectives: Determine whether antimicrobials are given judiciously in a tertiary care institution by assessing the pattern of antimicrobial usage.

A retrospective study was done to establish the current antibiotic prescribing practises at Tagore Medical College Hospital. A random sample of 100 inpatient case sheets from General Medicine, Obstetrics and Gynecology, General Surgery, Paediatrics, Chest Medicine, Skin, and ENT from the Medical Records Department were examined for antimicrobial delivery by oral and parenteral (IV) routes.

Males accounted for 53% of the participants in this study, while females accounted for 47%. The majority of the patients were in their forties and fifties (17-60yrs). A total of 16 antimicrobials were prescribed for 100 inpatients. The drugs Metronidazole and Ciprofloxacin were the most regularly utilised. The treatment lasted three days on average, thirteen days on average, and three days on average. The most common route of antibiotic delivery was parenteral because the patients were inpatients. Metronidazole (52%) was the most commonly used parenteral (IV) antibiotic, followed by Ciprofloxacin (42%), Cefotaxime (27%), Amikacin (7%), and Ceftriaxone (2%). (7 percent ). Sixty-three percent of the prescriptions were empirical, twelve percent were directed, and twenty-five percent were targeted.

Conclusions: Metronidazole and Ciprofloxacin were the most regularly used antimicrobials, with acute gastroenteritis being the most prevalent condition for which they were administered. The proportion of targeted prescriptions was low when compared to empirical prescriptions. Antibiotics must be prescribed judiciously and in compliance with the antibiotic policy.

Author(s) Details:

S. Priestly Vivekkumar,
Department of Pharmacology, Panimalar Medical College Hospital and Research Institute, Poonamalle, Chennai -123, India.


A. Aswin,
Department of Community Medicine, Indira Medical College, India

Balaji Arumugam,
Department of Community Medicine, Indira Medical College, India.

D. Jeyakumari,
Department of Microbiology, JIPMER, Karaikkal, India.

S. Kandasamy,
Department of Microbiology, Bharaath Medical College Hospitals, India.

 

Please see the link here: https://stm.bookpi.org/CAPRD-V9/article/view/5972

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