Determination of Lipid Profile and Atherogenic Indices for Cardiovascular Disease Risk Based on Different Fish Consumption Habits| Chapter 7 | Challenges and Advances in Pharmaceutical Research Vol.1

The ingestion of moderate amounts of fish on a regular basis is linked to a lower risk of death from cardiovascular disease (CVD). However, due to the oxidation susceptibility of the polyunsaturated fatty acids in fish, the positive effects of a fish-enriched diet appear to be paradoxical. The atherogenic index is a useful measure for identifying patients who are at risk for cardiovascular disease. Certain fish dietary habits have a positive effect on lipid profile levels, lowering the risk of coronary heart disease. The goal of this study was to assess CVD risk using atherogenic indices and to examine the plasma lipid profile of healthy persons with various fish intake habits.

Methods: Healthy people's fasting blood samples were taken for lipid profile calculations using an automated analyzer. Each participant provided detailed information on their physical and atherogenic characteristics.

Conclusions: The CVD risk profiles varied depending on the type of fish consumed. Total cholesterol, triglyceride (TG), and non-high-density lipoprotein (Non-HDL-C) levels differed substantially (p0.05), whereas high-density lipoprotein cholesterol levels differed considerably (p0.001). Inland fish consumers had a higher level of TG/HDL. The atherogenic coefficient and the Castelli risk index-2, on the other hand, did not differ significantly depending on the type of fish consumed. All fish eaters, including beef eaters, had atherogenic indices that were borderline "high risk."

Conclusion: People who ate fish and beef were at a higher risk than those who ate inland and sea fish. Non-HDL cholesterol may be a marker for a lipid profile in the blood linked to an elevated risk of heart disease. Non-HDL-C levels were borderline high risk for CVD in all fish, including beef eaters. There were age and sex-related differences in the TC and lipid-protein fractions. TC and LDL-C values were greater in women than in men. Non-HDL-C and TG/HDL-C levels can be utilised as more accurate indicators of CVD risk.

Author(s) Details:

Chandravathani Devadawson,
Department of Zoology, Faculty of Science, Eastern University, Chenkalady, Sri Lanka.



Chamila Jayasinghe,
Department of Food Science and Technology, Faculty of Livestock, Fisheries and Nutrition, Wayamba University of Sri Lanka, Makandura, Gonawila, Sri Lanka.



Sivakanesan Ramiah,
Department of Biochemistry, Faculty of Medicine, University of Peradeniya, Sri Lanka.

Arulnithy Kanagasingam,
Cardiologist Unit, Teaching Hospital, Batticaloa, Sri Lanka.

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