Understanding Dementia: Its Upcoming Issues and their Interlinking | Chapter 13 | New Frontiers in Medicine and Medical Research Vol. 11

 Because of the ageing population, risk factors for dementia have received a lot of attention in recent years. More research has been done on environmental, cardiovascular, and genetic variables. These risk variables can be strongly altered by the age and gender of the population investigated, with the likelihood of dementia growing in lockstep with age, and women experiencing more cognitive impairment in adulthood. Nutritional variables have also gotten a lot of attention, with studies showing that central obesity, hypercholesterolemia, and diabetes enhance neuroinflammation, increasing the risk of dementia and degenerative disorders like Parkinson's disease. Several genetic variants, such as the MAPT gene, have been linked to an increased risk of dementia, but mutations in APOE E4, a cholesterol carrier, have been linked to an increased risk of dementia, particularly in Alzheimer's disease. Due to increased conversations regarding the ethical and legal aspects involved, legal and financial interdictions, choices on medical proposals (such tracheostomy and enteral feeding), and self-management capacity decisions, such dementing and degenerative cases are also garnering attention. Recent research has emphasised the relevance of early detection, hereditary factors, and metabolic dysfunction prevention in providing a better prognosis for patients in their later years of life.

Author(S) Details

Arthur O. Schelp
Department Neurology, Psychology and Psychiatry; São Paulo State University, Botucatu, SP, Brazil.

Igor de Le Teixeira
Department Neurology, Psychology and Psychiatry; São Paulo State University, Botucatu, SP, Brazil.

Silvia J. Papini
Department Nursing São Paulo State University, Botucatu, SP, Brazil.

Jessica E. Komuro
Department Nursing São Paulo State University, Botucatu, SP, Brazil.

Andreas B. Schelp
São Paulo State Public Servant Hospital - IAMSPE, Sao Paulo, SP, Brazil.

João V. M. Lisboa
Department Neurology, Psychology and Psychiatry; São Paulo State University, Botucatu, SP, Brazil.

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