The purpose of this study was to compare the blood flow velocities in the Ophthalmic Artery, Central Retinal Artery, and Short Posterior Ciliary Arteries in patients with POAG and healthy subjects using Color Doppler Imaging, as well as to assess the effect of lowering intraocular pressure in POAG patients on retrobulbar blood flow.
Background: Raised
intraocular pressure (IOP) is one of the risk factors for Primary Open Angle
Glaucoma, according to the current definition. Another risk factor has been
linked to changes in ocular blood flow. Furthermore, the eye being treated for
glaucoma could be part of a larger systemic failure of auto-regulation of
ocular blood flow. The designation of normal tension glaucoma as a clinical
entity, as well as the observation of progressive glaucomatous damage despite
IOP management, support this notion. The goal of this study was to look at
retrobulbar blood flow in glaucoma patients using colour Doppler imaging (CDI)
and evaluate how IOP control altered these parameters.
This is a
prospective cohort study with 43 newly diagnosed POAG patients and 30 healthy
controls. The ocular artery (OA), central retinal artery (CRA), and short
posterior ciliary arteries were investigated for peak systolic velocity (PSV),
mean end diastolic velocity (EDV), and resistivity index (RI) (SPCA). The
results were compared to those of healthy individuals and patients with POAG
before and after treatment.
Only in patients
with POAG were mean PSV and EDV observed to be significantly lower in OA and
CRA as compared to controls. Blood flow characteristics were identical to
non-glaucomatous eyes once the goal pressure was reached.
Author(S) Details
C. Sharma
Royal Derby Hospital, UK.
R. Saini
Royal Derby Hospital, UK.
M. D. Singh
Department of Ophthalmology Atal Bihari Vajpayee Institute of Medical Sciences and Dr. RML Hospital, New Delhi, India.
View Book:- https://stm.bookpi.org/NFMMR-V11/article/view/3703
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