The current study is expected to provide a better understanding of the global distribution of significant human fungal infections, serve as a reference for future research, and help to the improvement of public health in the region's fungal diseases. As ever-more advanced healthcare systems create more risk factors, fungal infections (mycoses) are anticipated to become more common. In Malaysia, there are few comprehensive statistics on the incidence and prevalence of human fungal infections. In order to determine the burden of severe fungal infections in Malaysia, we conducted a detailed investigation. Recurrent vaginal candidiasis (>4 episodes/year) was shown to be the most common of all cases with a candidiasis diagnosis (n = 501,138). Oesophageal candidiasis (n = 5850) was the most common infection among HIV patients. The incidence of candidemia was assessed in hospitalised patients (n = 1533), some of whom were receiving cancer therapy (n = 1073), and it was also discovered in patients admitted to intensive care units (n = 460). Atopic bronchopulmonary aspergillosis (ABPA) was the second most prevalent respiratory mycoses found in adults with asthma (n = 30,062), followed by severe asthma with fungal sensitivity (n = 39,628). Invasive aspergillosis was found in 184 patients receiving anti-cancer treatment and 834 patients in intensive care units. In 700 HIV/AIDS patients, cryptococcal meningitis was discovered, while Pneumocystis jirovecii pneumonitis (PCP) was discovered in 1286 HIV patients. According to the current study, at least 590,214 Malaysians (1.93 percent) are infected by a significant fungal illness each year. This is a major problem that necessitates more epidemiological research to determine the extent of human fungal infections in Malaysia.
Author(s) Details:
Rukumani Devi Velayuthan,
Department of Medical Microbiology, Faculty of Medicine, University of
Malaya, Kuala Lumpur 50603, Malaysia.
Chandramathi Samudi,
Department of Medical Microbiology, Faculty of Medicine, University of Malaya,
Kuala Lumpur 50603, Malaysia.
Harvinder Kaur Lakhbeer Singh,
Department of Medical Microbiology, Faculty of Medicine, University of Malaya,
Kuala Lumpur 50603, Malaysia.
Kee Peng Ng,
Department of Medical Microbiology, Faculty of Medicine, University of Malaya,
Kuala Lumpur 50603, Malaysia.
Esaki M. Shankar,
Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine,
University of Malaya, Kuala Lumpur 50603, Malaysia and Department of
Microbiology, School of Basic & Applied Sciences, Central University of
Tamil Nadu (CUTN), Thiruvarur 610 101, Tamil Nadu, India.
David W. Denning,
Faculty of Biology, Medicine and Health, The University of Manchester and
Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9PL, UK
and The National Aspergillosis Centre, Education and Research Centre,
Wythenshawe Hospital, Manchester M23 9LT, UK.
Please see the link here: https://stm.bookpi.org/IMB-V4/article/view/6225
No comments:
Post a Comment