In the present study, effect of Heterometrus
fastigiousus Couzijn (Family: Scorpionidae) venom on
alkaline phosphatase (ALP), acid
phosphatase (ACP), lactic dehydrogenase (LDH) and glutamatepyruvate
transaminase (GPT) enzyme activity, and
red blood cells (RBCs) count, white blood cells
(WBCs) count, blood hemoglobin, mean
corpuscular hemoglobin (MCH), packed cell volume (PCV)
and plasma hemoglobin in experimentally
envenomed albino mice was studied. Venom was obtained
by electrical stimulation and its
toxicity was determined in albino mice by subcutaneous
envenomation. The LD50 was 18.6 mg kg-1
body weight of mice. H. fastigiousus venom caused
significant increase in ALP, ACP, LDH and
GPT activity in liver tissue of albino mice. This venom
reduced RBC count and increased WBC
count, blood hemoglobin, MCH, PCV and plasma
hemoglobin. Findings of this study will
help to understand the mechanism of Asian black scorpion,
H. fastigiousus venom toxicity.
Author (s)
Details
Mukesh Kumar Chaubey
Department
of Zoology, National Post Graduate College, Barhalganj, Gorakhpur - 273402,
Uttar Pradesh, India.
View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/239
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