An Introduction to Base Editing and Prime Editing: Principles and their Importance | Chapter 13 | Research Developments in Medicine and Medical Science Vol. 5

 The present study present readers to the concepts and law  of “Base  editing” and “Prime rewriting” – two very important methodologies  that almost revolutionized the field of Genome  Editing over ancient times few years. Prime editing shows taller or similar adeptness and fewer byproducts than homology-supervised repair, has complementary substances and weaknesses compared to base refining, and induces much lower off-target rewriting than Cas9 nuclease at known Cas9 off-target sites. Prime rewriting substantially expands the purview and capabilities of genome editing, and in standard could correct until 89% of known genetic variations associated with human ailments.

Author(s) Details:

Alex Sobko,
Department of Molecular Cell Biology, Weizmann Institute of Science (WIS), Rehovot, 76100, Israel. #PhD. 8762728, Ofakim, Israel.

Please see the link here: https://stm.bookpi.org/RDMMS-V5/article/view/9967