Identification of Chemical Constituents of Artocarpus odoratissimus from Sarawak| Chapter 3 | Recent Progress in Chemical Science Research Vol. 6

 Artocarpus class contain a extreme concentration of phenolic compounds, to a degree flavonoids, stilbenoids, and arylbenzofurons. Furthermore, compounds from Artocarpus species demonstrated decontaminating, antitubercular, antiviral, antifungal, antiplatelet, antiarthritic, tyrosinase inhibitory, and cytotoxic properties. However, skilled has been no phytochemical research on Artocarpus odoratissimus from Sarawak. As a result, it hopeful intriguing to build a chemical profile of aforementioned Sarawakian species. Various chromatographic designs, including liquid emptiness chromatography, radial chromatography, and procession chromatography, were used to isolate the synthetic constituents of Artocarpus odoratissimus' root, bark, and leaves. The leaves can also be used to recover ulcers and burn.  The seclusion and purification utilizing different solvent system ratio of hexane and ethyl acetate (10:0, 8:2, 6:4, 4:6, 2:8, 0:10) and ethyl acetate and intoxicating (8:2) have led to two flavonoids; pinocembrin (1) and pinostrobin (2), and six triterpenoids; α-amyrin acetate (3), β-amyrin acetate (4), traxateryl acetate (5), hexyl dodecanoate (6), β-sitosterol (7) and stigmasterol (8). The makeups (1) – (8) were elucidated using differing spectroscopic analyses, that included Mass Spectroscopy (MS), Infrared (IR) spectroscopy, Ultra-lilac (UV) spectroscopy and Nuclear Magnetic Resonance (NMR) spectroscopy, as well as by comparison accompanying the reported dossier. Although the presence of compounds 1 and 2 was governing across a wide range of plant variety, it was rare in Artocarpus species, that may have chemotaxonomic associations for the genus Artocarpus.

Author(s) Details:

Khong Heng Yen,
School of Chemistry and Environmental Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, 94300 Kota Samarahan, Sarawak, Malaysia.

Nyotia Nyokat,
School of Chemistry and Environmental Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, 94300 Kota Samarahan, Sarawak, Malaysia.

Clifford Junaidi Kutoi,
School of Chemistry and Environmental Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, 94300 Kota Samarahan, Sarawak, Malaysia.

Ahmad Sazali Hamzah,
Institute of Science, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia.

Isabel Fong Lim,
Department of Paraclinical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Malaysia.

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