Estimation of Cellular Content in Second-Generation Solid Fibrin Concentrates (PRFs)| Chapter 6 | Cutting Edge Research in Biology Vol. 4

 We acted a study to judge the amount of Platelets and Leukocytes directly-production hard platelet concentrates in conditions of Sensitivity, Specificity, Positive Predictive Value (VP+), Negative Predictive Value (VP-), False Negative Proportion, and False Positive Proportion of our Statistical Method. Blood was composed in anticoagulant-free PET tubes accompanying silica for clot result and PRF membranes. The membranes and clots presented were checked. In a premature work, the authors, offset from the results acquired in Kitamura's work, cherished to evolve an smooth and modest order to reckon the exact amount of platelets and leukocytes held in PRF, distinguished to the individual present in unmodified blood, offset from a plain "haemochromocytometric test". In this study, the authors have judged the Sensitivity, Specificity, Positive Predictive Value (VP+), Negative Predictive Value (VP-), False Negative Proportion, and False Positive Proportion of the "Statistical Method". Using the Statistical Method, we have this result by lowering by 34.12% (±28.2) the profit of leukocytes got from the CBC test. We acquired the profit of leukocytes held in the PRF sheath by t-PA digesting and by lowering by 15.12% (±24.87) the worth of platelets got for one alike arrangement, we have attained the profit held in dimensional platelet concentrates by t-PA digesting. The projected order confirmed a Se=0.75; Sp=0.86; VP+=0.75; VP-=0.86 for platelet counts, Se=0.47; Sp=0.66; VP+=0.80; VP-=0.30 for blood corpuscle counts. Conclusion: Our study reliable to similar the PRF arrangement process by approving a mathematical arrangement to reckon the exact amount of platelets and leukocytes in second-era dependable platelet concentrates, making it smooth to judge individual PRF arrays according to schedule in the dispassionate scene. The Statistical plan distinguished to the digestive order accompanying t-PA for blood corpuscle and platelet counts confirmed expected evenly right for platelets, but not also for leukocytes.

Author(s) Details:

Michela Crisci,
General Surgery, Faculty of Medicine and Surgery, Vasile Goldis Western University of Arad, 310025 Arad, Romania.

Alessandro Crisci,
School of Medicine, University of Salerno Italy, 84084 Fisciano SA, Italy and Unit of Dermosurgery Cutaneous Transplantations and Hard-to-Heal Wound, 'Villa Fiorita' Private Hospital, 81031 Aversa CE, Italy.

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