At the Tambool slaughter house, hydatid cysts were excised from camel livers and lungs, and protoscoleces were separated aseptically. Thirty 6-week-old Swiss mice (25-30 gramme body weight males) were put into two groups of six mice each: a prophylactic group received 150 ml/kg albendazole, and a mebendazole group received mebendazole immediately after injection with 2000 protoscoleces intraperitoneally for 10 days. The most commonly recommended antibiotics for intestinal worm infections are albendazole and mebendazole. The treated group received 300 mL/kg albendazole and mebendazole every 4 days, separated by 2 days, for 24 days, and the two groups, along with the control group, were slaughtered and necropsied after 6 months following protoscoleces inoculation. The data demonstrated a significant variation in hydatid cyst formation. When comparing the groups treated with albendazole and mebendazole to the control group, a small number of cysts were found inside the mice; however, albendazole was more effective than mebendazole, with albendazole reaching 97 percent efficiency and mebendazole reaching nearly 50 percent efficiency. This shows that albendazole may be the best option for hydatid cyst treatment.
Author(s) Details:
Ekram Ismail Fagiree Ismail,
Department of Biology, College of Science, University of Hafr Al Batin,
Saudi Arabia. Alzaiem Al Azhari University, Sudan.
Mohammed Bahaa Eldeen Ahmed Saad,
Department of Parasitology, College of Medical Laboratory, Omdurman Alahlia
University, Khartoum, Sudan.
Aisha Abass Elsadig,
Department of Radioisotopes of the Veterinary Research Center, Khartoum, Sudan.
Please see the link here: https://stm.bookpi.org/NVBS-V10/article/view/5982
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