The goal of this work is to utilise bibliometric approaches to assess recent 10-year trends in immunotherapy research in breast cancer, resulting in a better understanding of the present status and trends of those research papers by analysing their primary characteristics. Many research in recent years have focused on the host immune system and its role in tumour growth in a range of solid tumours, including breast cancer. This paper explores contemporary trends in immunotherapy research in breast cancer and compares research contributions from various countries, institutions, and authors. The Web of Science database was searched for breast cancer and immunotherapy research published between 2010 and 2019 using various keyword combinations. For analysis, bibliometric data were gathered. To implement network visualisation study, VOSviewer software was utilised to build a figure for the keyword's co-occurrence network. There were a total of 1,041 publications found. The United States and China generated 336 and 208 publications, respectively, accounting for over half of all publications. Following 2015, both countries spearheaded the increase in publications. The most referenced paper was Nanda et al"Pembrolizumab .'s in Patients with Advanced Triple-Negative Breast Cancer: Phase IB KEYNOTE-012 Study" published in the Journal of Clinical Oncology (715 citations). The keywords discovered in this study were divided into four categories: "mechanism," "vaccination," "PD-L1," and "chemotherapy." The phrases "tumor-infiltrating lymphocytes" and "PD-1/PD-L1" are among the most recent hotspots, appearing largely in 2017. Recent developments in breast cancer immunotherapy have focused on the triple-negative breast cancer subtype and the PD-1/PD-L1 immune checkpoint pathway and inhibitors, according to author keyword analysis. This study examined global trends in breast cancer immunotherapy research over the last decade and gave insight into the features and research hotspots of the articles in this issue.
Author(S) Details
Soo Kyung Ahn
Department of Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.
Ji Woong Hwang
Department of Surgery, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Seoul, Gwangmyeong, Republic of Korea, South Korea.
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