Children with Asthmatic Exacerbation Influences of Different Phenotypes| Chapter 1 | Perspective of Recent Advances in Medical Research Vol. 5

 Asthma exacerbations are outlined as an acute or subacute worsening of syndromes and lung function concerning the usual conditions of the patient. Asthma is a assorted disease and various phenotypes have been identified.Objective: To see the epidemiological and clinical profile of pediatric inmates hospitalized for unable to respire normally exacerbations in a highly complex metropolitan emergency room.Methods: A retrospective explanatory study that included all children old between 4 to 14 age with a diagnosis of intensification or asthmatic crisis sick in one period period was performed. The dispassionate records were reviewed, and mathematical and clinical history particularly directed to identified various phenotypes and comorbidities were analyzed.Results: Fifty unable to respire normally children met the addition criteria. Prior to treatment, 66% had moderate asthma, and 10% had severe asthma. Persistent rhinitis was found in 66%, and 40% had a annals of at least one former hospitalization for asthma attacks, place 20% had been hospitalized accordingly in the last year and 18% had not completely one previous regimen in the ICU or CPU. Only 70% of the patients had a earlier established diagnosis of asthma and 28% had able compliance with two together treatment and attendance at healing controls. On admission, 20% were obese. In 54% of the cases, individual or both persons reported smoking all along the research period. Symptoms duration superior to admission was inferior 24 hours in 40% of the patients, and 34% could be delineated with doubtful asthma. Twenty two percent of the patients were conceded to the ICU or CPU, of which 45% started their symptoms in less than 24 hours and 36% more can be defined as bearing unstable asthma.Conclusions: We raise a group of patients who, in spite of not presenting syndromes and apparent clinical signs of harsh asthma, some of them accompanying a history of premature hospitalizations, suddenly presented an unable to respire normally exacerbation that progressed in a few hours with respiring failure and requiredadmission to hospital ICU or CPU. Further description is necessary for the instruction, management, and personalized situation of this group cause they resemble a different phenotype earlier described as type II labile asthma in men.

Author(s) Details:

Isabel Gárate,

Children´s Hospital Dr. Exequiel González Cortés, Santiago de Chile, Chile.

Guido Girardi,

Department of Pediatrics, School of Medicine University of Chile, Santiago de Chile, Chile.

María Angélica Pérez,

Department of Pediatrics, School of Medicine University of Chile, Santiago de Chile, Chile.

Arnoldo Quezada,

Department of Pediatrics, School of Medicine University of Chile, Santiago de Chile, Chile.

Please see the link here: https://stm.bookpi.org/PRAMR-V5/article/view/9137