Thursday, 3 March 2022

Determining the Anthelmintic Activity of Extracts of Aerial Parts of Tephrosia spinosa (L.f.) Pers| Chapter 5 | Current Aspects in Pharmaceutical Research and Development Vol.9

 The goal of this study is to see if Tephrosia spinosa (L.f.) Pers has any anthelmintic activity on Indian earthworms. It's a prickly, stiff plant that's abundant in southern India.

Methods: Anthelmintic activity of chloroform and methanol extracts of T. spinosa in Indian earth worms (Pheretima posthuma) was examined using albendazole (10 mg/ml) as a standard reference and normal saline as a control. The amount of time it took to paralyse and kill the worms was estimated.

The aerial portions of T. spinosa (L.f.) Pers had substantial anthelmintic action (p0.001) when compared to albendazole.

Tephrosia spinosa exerts a paralytic impact on Indian earth worms, according to the findings.

Author(s) Details:

K. Ilango,
Department of Pharmaceutical Chemistry, College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur - 603 203, Chengalpattu (Dt), Tamil Nadu, India.

R. Xavier Arulappa,
Department of Pharmaceutical Chemistry, S.A. Raja College of Pharmacy, Vadakankulam – 627 116, Tirunelveli (Dt), Tamil Nadu, India.

Please see the link here:
https://stm.bookpi.org/CAPRD-V9/article/view/5965

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