Antiplasmodial Potentials and GC-MS Analysis of Bioactive Compounds in Methanol and Ethanol Leaf Extracts of Daniellia oliveri | Chapter 7 | Research Advances in Microbiology and Biotechnology Vol. 7

 The aim of the study was to resolve D. oliveri utilizing qualitative, all-inclusive, and Gas Chromatography-Mass Spectroscopy (GC-MS) analytical systems to screen for phytochemical components and determine bioactive essences. The information concerning phytochemical compounds are not only supportive for finding of therapeutic potential, but also have an alive contribution towards finding of new semi-synthetic and artificial compounds. The identification of bioactive details required for evaluating the antiplasmodial potentials of flammable liquid and ethanol leaf extracts of Daniellia oliveri (D. oliveri) concede possibility be accomplished by subjective, quantitative, and Gas Chromatography-Mass Spectrometry (GC-MS) analyses. The leaves were composed in Anyigba, Kogi state from which intoxicating and ethanol extracts were prepared, phytochemical parts detected and bioactive compounds driven using GC-MS. Results demonstrated the presence of alkaloid, tannin, reducing carbohydrate, saponin, terpenoid, phenol, cardiac glycosides and flavonoid in the extracts. Phenol showed the maximal concentration (46.14 and 43.09 mg/100g) while terpenoid showed hostile concentration (10.63 and 9.97 mg/100g) in intoxicating and ethanol extracts respectively. GC-MS study revealed the closeness of higher elements (57) in methanol extract compared to intoxicating extract (27). This study provides controlled evidence that methanol may be a better ancestry solvent for GC-MS reasoning of D. oliveri leaves meant expected used for the determination of antiplasmodial endeavor than ethanol on account of higher components discovered in methanol extract distinguished to ethanol extract.

Author(s) Details:

Muhammed Muazu,
Pharmacology Laboratory, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Abdulsalami Mohammed Sani,
Department of Biotechnology, Nigerian Defence Academy, PMB 2109, Kaduna, Nigeria.

Karderam Bukar Dikwa,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Deborah Madi Dibal,
Department of Biological Sciences, Nigerian Defence Academy Kaduna, Nigeria.

Kokori Bajeh Tijani,
Department of Pharmacology, Faculty of Basic Clinical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Junaidu Yahaya,
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Kogi State University, Anyigba, Nigeria.

Please see the link here: https://stm.bookpi.org/RAMB-V7/article/view/12177