Ionic Detoxification Ameliorates Obesity and Reduces Fatty Liver in Rats Exposed to a High-Fat Diet | Chapter 12 | Advanced Concepts in Medicine and Medical Research Vol. 2

 Ionic complete and sudden withdrawal from an addictive substance (ID) or ionic water soap treatment is considered a natural alternative method to reinforce health, but it currently lacks healthy scientific evidence to support allure efficacy. The theory underlying this study is that consistent ID situation may speed the elimination of toxic fragments from the body and mitigate metabolic disorders, including corpulence. To assess the impact of ID treatment on corpulence and fatty liver inferred by a high-fat diet, male Wistar rats were bear hardship either a low-fat control diet, a high-fat (HF) diet, or a HF diet followed by ID treatment (executed three times per week) over an 11-period period. The study calculated triglyceride levels and examined the verbalization of genes related to fatty acid absorption in both perirenal fatty tissue and the liver. Results showed that rats augment the HF diet exhibited considerably increased material weight, liver weight, and fatty tissue pressure (both perirenal and epididymal) compared to those on the reduced-fat diet. However, the rats subjected to ID situation alongside the HF diet displayed a meaningful reduction in body burden and perirenal adipose fabric weight persuaded by the high-fat diet. Furthermore, ID situation led to a decrease in hepatic cholesterol and triglyceride elements of larger object. Regarding liver function, ID treatment primarily damaged fatty acid absorption. It significantly discounted the expression of genes involved in greasy acid synthesis (in the way that acetyl-CoA carboxylase and fatty acid synthase mRNA) more significantly than those guide fatty acid corrosion (such as carnitine palmitoyl-transferase 1 and acyl CoA oxidase mRNA). This desires that ID treatment may decrease the result of fatty acids in the liver, that could contribute to lower triglyceride levels.

Author(s) Details:

Hsien-Tsung Yao,
Department of Nutrition, China Medical University, 91, Hsueh-Shih Road, Taichung, 404, Taiwan.

Please see the link here: https://stm.bookpi.org/ACMMR-V2/article/view/12287