Thursday, 26 October 2023

Challenges in the Biomedical Treatment of Down Syndrome | Chapter 3 | Advanced Concepts in Medicine and Medical Research Vol. 1

 The branch examines the being of treating persons accompanying Down syndrome (DS) physiologically alternatively only via laboratory analyses. Human chromosomal or gene situation is loaded accompanying logistical and moral challenges. In every container in the human body skilled is a nucleus, place genetic material is stored in genes. Genes bear the codes responsible for all of our hereditary traits and are grouped near rod-like buildings called chromosomes. Typically, the core of each cell contains 23 pairs of chromosomes, half of that are inherited each parent. Down syndrome happens when an individual has a full or incomplete extra copy of chromosome 21. To prevent DS, genome rewriting would have to be performed inappropriate embryos. In vitro findings point toward the feasibility of silencing extra deoxyribonucleic acid 21 (C21) in later embryonic or foetal life, or even postnatally for few aspects of neurogenesis. These potential are beyond what is allowed contemporary. Another approach is through regulating the overexpression of injurious genes on C21. Research with rodent models of DS is yielding promising results. Human requests have barely started and are questioned on ethical sediments.

Author(s) Details:

Jean A. Rondal,
University of Liège, Belgium.

Please see the link here: https://stm.bookpi.org/ACMMR-V1/article/view/12290

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