Clinical Characteristics and Outcomes of Diabetic Ketoacidosis among COVID-19 Patients: A Study at Suhar Hospital, Oman | Chapter 7 | Novel Research Aspects in Medicine and Medical Science Vol. 8

 This study's objective search out investigate the predominance, clinical traits, and consequences of DKA and COVID-19 patients sick to Suhar Hospital in Oman. Diabetic ketoacidosis (DKA) is characterized by uncontrolled hyperglycemia, metabolic upset stomach, and increased physique ketone concentration. It is a life-threatening difficulty of diabetes and is usually visualized in patients with type-1 diabetes mellitus. Rarely it grant permission also happen in patients with type-2 diabetes mellitus. DKA is a state of a relative or categorical insulin deficiency namely worsened by hyperglycemia, dehydration, and upset stomach. In most cases, the trigger is an contamination, new-onset diabetes, or lack of agreement with treatment.  Diabetic ketoacidosis (DKA) is an severe complication with COVID-19 patients with diabetes mellitus (DM). It is establish to be a chief cause of poor prognostic indicators in COVID-19 inmates. A retrospective review of DKA victims admitted to Suhar Hospital, Oman, from March 2020 to August 2020. DKA patients will be top-secret as with or outside laboratory- confirmed COVID-19. SPSS, adaptation 22, was used to describe dossier (median, interquartile range-IQR and percentages) and to test for statistical distinctnesses at 5% significance level (u.s. city- square test, Fisher’s exact test and Mann-Whitney U-test). Twenty seven patients were found to accomplish the criteria of DKA. Of ruling class, 13 patients had rooted COVID representing a prevalence of 1.4%. COVID DKA victims compared to non-COVID were distinguished as being males (54% vs. 43%), older (36 vs. 22), lengthier on hospital stay (5 vs. 2), had T2DM (62% vs. 7%), confessed to ICU (46% vs. 7%) and higher in mortality (31% vs. 0%) in addition to clinically presented accompanying a low pH (7 vs. 7.2) and bicarbonate (6.2 vs. 11.1), high antitoxin creatinine (101.0 vs. 84.0) and CRP (34.0 vs. 4.8). Significant factors (p<0.05) raise to enhance mortality with COVID DKA patients were COVID pneumonia asperity, extensive bilateral radiological infiltrates, ICU admissions, machinelike ventilation, harsh metabolic acidosis and larger WBC and Neutrophils. All deceased COVID-19 DKA patients grown complications in the way that ARDS, renal failure, requiring hemodialysis and poisonous shock. This study emphasizes the link 'tween COVID-19 and DKA as well as the effects of allure 31% death rate and remote possibility characteristics. This highlights the union of COVID-19 and DKA among T2DM and extended hospital stay. Severe COVID pneumonia, severe metabolic upset stomach, ICU admissions, mechanical ventilations and extreme inflammatory markers were weak prognostic factors between COVID-19 patients admitted accompanying DKA.

Author(s) Details:

Ali Al-Reesi,
Consultant Endocrinologist, Head of Internal Medicine Department, Suhar Hospital, Ministry of Health, Oman.

Hamed Al-Reesi,
Head of Studies and Research Department, Directorate General of Planning and Studies, Ministry of Health, North Batinah Governorate, Oman.

Please see the link here: https://stm.bookpi.org/NRAMMS-V8/article/view/12186